Low-Carb, Moderate-Carb Diet and Type II Diabetes

Welcome to Worth-a-Word Wednesdays, where I review and summarise a study or article that I think provides some useful and interesting information. This week – Low carb vs moderate carb diet and type 2 diabetes.

Article Title: Twelve-month outcomes of a randomised trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or pre-diabetes.

This study was published by Saslow, L. R., et al. (2017) In Nutrition and Diabetes 7(12), 304.

Today we are talking about a 2017 study of Low-Carbohydrate Ketogenic diet (LCk) versus a Moderate Carbohydrate, Calorie Restricted, low-fat diet (MCCR) and type 2 diabetes.

Participants with type 2 diabetes, glycated haemoglobin (a form of haemoglobin that is chemically linked to sugar) >6.0% and increased body weight (BMI > 25) we randomly put into two groups, with different diets; LCK and MCCR.

After 12 months, the study found the following;

  • LCK group had a greater reduction in glycated haemoglobin.

  • Participants in the LCK group lost more weight (an average of 8kgs in LCK vs 1.7kgs in MCCR).

  • LCK group experienced a larger reduction in the amount of diabetes-related medication they required.

  • Specifically, of the participants who took sulfonylureas or dipeptidyl peptidase-4 inhibitors (diabetes related medication) at the beginning of the study, 6/10 in the LCK group discontinued use of these medications compared to 0/6 in the MCCR group.

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